产品货号:
Z11298
中文名称:
APC11/ANAPC11抗体
英文名称:
Anti-APC11/ANAPC11 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-APC11/ANAPC11 Antibody |
指标别名 | APC11;Apc11p;HSPC214;MGC882 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IF |
基因名称 | ANAPC11 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | APC11 antibody was raised against an 18 amino acid synthetic peptide near the center of human APC11.The immunogen is located within amino acids 70 - 120 of APC11. |
计算分子量 | 10kDa |
成分 | APC11 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | APC11 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis.APC11 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C),a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.APC/C is responsible for degrading anaphase inhibitors,mitotic cyclins,and spindle-associated proteins ensuring that events of mitosis take place in proper sequence.The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines,suggesting that they perform their functions as part of a complex.APC11,together with APC2 and Ubc4,form the minimal APC ubiquitin ligase module. |
Uniprot ID | Q9NYG5 |
基因名全称 | Anaphase promoting complex subunit 11 |
蛋白名全称 | Anaphase promoting complex subunit 11 |
推荐稀释比 | APC11 antibody can be used for detection of APC11 by Western blot at 1μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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